TLE1 IHC Test for Synovial Sarcoma | Lahalak Platform
IHC analysis for TLE1 protein helps confirm or rule out synovial sarcoma in soft tissues, ensuring the development of an effective and early treatment plan.
Scientific name: Immunohistochemistry: TLE1
Immunohistochemical (IHC) testing reveals the nuclear expression of TLE1 (transducin-like enhancer of split 1). Strong nuclear expression of TLE1 is a highly sensitive and specific marker for synovial sarcoma, a malignant stromal tumor that most commonly arises in the extremities near joints. TLE1 is a transcription factor that aids in predicting t...
Service type
Laboratory test (Tissue Biopsy)
Duration
10-15 minutes
Fasting
Fasting is not required
Included Services
- Detailed analysis to detect nuclear expression of the TLE1 protein in tumor tissue samples.
- Consult a pathologist specializing in soft tissue tumors to interpret the results.
- Personal support services from Halak.
Medical Service Information
Conditions & Notices
- The analysis does not require the patient to fast, as it is performed on a fixed tissue sample.
- The need for a sufficient tumor tissue sample (preferably an excisional biopsy or a centrifugal needle biopsy).
- It is strongly recommended that it be performed as part of a diagnostic panel for soft tissue tumors, and may require confirmation by FISH testing to detect t(X;18) chromosomal translocation in critical or atypical cases.