P53 IHC Tumor Genome Testing | Lahalak Platform
Advanced analysis to evaluate mutations in the P53 gene, providing valuable information on tumor aggressiveness and prognosis, while guiding necessary genetic counseling for cancer patients and their families.
Scientific name: Immunohistochemistry (IHC) for P53
Immunohistochemical assays for p53 aim to assess the status of the p53 protein, a nuclear transcription factor that acts as a guardian of the genome and inhibits tumorigenesis. IHC reveals the accumulation of mutant (non-functional) p53 protein within the nucleus, or the absence of the protein in the case of certain loss-of-function mutations. The...
Included Services
- Detailed analysis to assess the expression pattern of the P53 protein in tumor tissue samples
- Consult a pathologist or cancer geneticist to interpret the results.
- Personal support services from Lahalak
Medical Service Information
Conditions & Notices
- Fasting is not required, as the sample is tissue-based.
- The tissue sample must be immediately preserved in 10% formalin.
- This analysis is increasingly requested in the comprehensive evaluation of many solid tumors, particularly high-grade ovarian tumors, triple-negative breast tumors, and central nervous system tumors.
- It is often requested as part of molecular or predictive tumor characterization packages.