ALK-1 Protein Test Price | Lahalak Platform
Histological examination to detect abnormal ALK-1 protein expression, a vital biomarker for identifying tumors eligible for targeted ALK inhibitor therapy for better outcomes.
Scientific name: Immunohistochemistry (IHC) for ALK-1 Protein
A qualitative immunohistochemical (IHC) assay using a monoclonal antibody (usually Clone D5F3 or ALK1) against anaplastic lymphoma kinase (ALK) on tissue slides. It aims to detect aberrant ALK protein expression resulting from gene rearrangements or amplification, and is a therapeutic biomarker in several tumors.
Service type
Immunohistochemical Tissue Test
Duration
20-30 minutes
Fasting
Fasting is not required
Included Services
- Prepare a tissue slide and perform immunofixation using a highly sensitive, specific antibody for the ALK protein (Clone D5F3 recommended).
- Accurate assessment of ALK staining intensity and pattern in tumor cells using a standardized scoring system.
- Consult a pathologist or oncologist to interpret the results.
- Personal support services from lahalak.
Medical Service Information
Conditions & Notices
- Essential requirement: A high-quality, representative FFPE tissue mass of the tumor is available. Small or poorly processed biopsies may give false-negative results.
- The examination must be preceded by a preliminary histological diagnosis (H&E).
- The laboratory must be informed of the type of tumor suspected (lung, lymphoma, etc.) because the interpretation criteria may vary.
- Positive results (2+/3+) in lung cancer require confirmation by FISH testing before starting targeted therapy.
- Delivery time: 5-7 business days.
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