CDX2 Tumor Origin Test | Lahalak Platform
A precise diagnostic kit used to determine the histological origin of metastatic cancers, guiding physicians toward the most effective treatment based on the primary site.
Scientific name: Immunohistochemistry (IHC): CDX2
This diagnostic package, based on immunohistochemistry, involves testing for a range of markers to determine the origin of cancerous metastases. The package primarily includes testing for CDX2, a nuclear transcription factor expressed in the nuclei of normal and cancerous epithelial cells in the small intestine and colon, as well as the essential c...
Service type
Laboratory test (Tumor Markers)
Duration
10-15 minutes
Fasting
Fasting is not required
Included Services
- CDX2 specific transcription factor testing to detect intestinal origin.
- Examination of the two complementary cytokeratin markers CK20 and CK7 to determine the epithelial pattern.
- The PAX8 marker test helps to rule out or confirm an origin from the ovary, uterus, or kidneys.
- Consult a pathologist specializing in gastrointestinal tumors or metastatic tumors for interpretation of the overall results.
Medical Service Information
Conditions & Notices
- It requires the submission of a complete tissue block (paraffin block) from the metastatic or tumor specimen of unknown origin.
- It is necessary to attach the initial pathology report, the location of the metastatic sample, and any prior history of cancer, if any.
- The patient does not need to fast, as the sample is tissue-based.
- The completion time ranges from 5 to 10 working days.
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