Safe Anesthesia Screening Test

Dibucaine Inhibition Number Test

Planning for surgery? This test identifies genetic variants affecting anesthesia metabolism, helping prevent prolonged respiratory issues after surgery for a safer and more predictable surgical experience for you.

Trusted medical contentUpdated: 10-11-2026Views: 0LHL-6654

Frequently Asked Questions

Short answers to the FAQs published with this service.

• What is the Dibucaine Number?

It is a measure of how much dibucaine inhibits cholinesterase activity, identifying the genetic variant of the enzyme.

• Why is this test ordered before surgery?

To ensure your body can metabolize anesthesia drugs normally and avoid prolonged respiratory paralysis.

• Is fasting required for this test?

No, fasting is not required for the Dibucaine Inhibition Number test.

• Can I take this test at home?

Yes, home blood collection service is available for this test through Lahalak Medical Platform.

• What does a low dibucaine number mean?

It indicates a genetic variant that makes the patient highly sensitive to certain muscle relaxants used in anesthesia.

• Is this test necessary for children?

It is recommended for children with a family history of anesthesia issues or before specific surgical procedures.

Medical Laboratories

Safe Anesthesia Screening Test

Dibucaine Inhibition Number Test

Trusted medical contentUpdated: 10-11-2026Views: 0LHL-6654

View service availability

Service typeLaboratory test

Duration10-15 minutes

Fasting / preparationFasting is not required

Home serviceAvailable

Medical notice: this information is for education and service understanding. It is not a diagnosis or a recommendation for an unnecessary procedure.

About this service

A laboratory assay measuring pseudocholinesterase inhibition by dibucaine. It identifies genetic variants causing prolonged apnea after muscle relaxants, ensuring patient safety during and after general anesthesia.

Clinical Significance

Identifies risk of prolonged apnea following general anesthesia.
Detects genetic variants of the pseudocholinesterase enzyme.
Assists anesthesiologists in selecting safe muscle relaxants.

When is this test recommended?

Prior to elective surgeries requiring general anesthesia.
If a family member has experienced anesthesia complications.
To screen for succinylcholine sensitivity.

Understanding Your Results

Normal (Above 70): Indicates typical enzyme activity and low risk.
Intermediate (40-70): Suggests a heterozygous genetic variant.
Low (Below 30): Indicates homozygous variant and high sensitivity to relaxants.

What is included?

✓Venous blood sample collection
✓Cholinesterase activity measurement
✓Dibucaine inhibition percentage calculation

Conditions and notices

Fasting is not required
Inform the doctor of any family history of anesthesia complications
Avoid testing immediately after major surgeries

Frequently Asked Questions

Short answers to the FAQs published with this service.

• What is the Dibucaine Number?

It is a measure of how much dibucaine inhibits cholinesterase activity, identifying the genetic variant of the enzyme.

• Why is this test ordered before surgery?

To ensure your body can metabolize anesthesia drugs normally and avoid prolonged respiratory paralysis.

• Is fasting required for this test?

No, fasting is not required for the Dibucaine Inhibition Number test.

• Can I take this test at home?

Yes, home blood collection service is available for this test through Lahalak Medical Platform.

• What does a low dibucaine number mean?

It indicates a genetic variant that makes the patient highly sensitive to certain muscle relaxants used in anesthesia.

• Is this test necessary for children?

It is recommended for children with a family history of anesthesia issues or before specific surgical procedures.

Service resources and references

References and additional resources

Reference material and files associated with this service when available.

Scientific references

American Association for Clinical Chemistry (AACC)
Mayo Clinic

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Important Notice:

Content on LahaLak is provided for educational purposes only. It is not a medical diagnosis, prescription, or substitute for consulting a qualified clinician. Medical decisions should not be made from this content alone.

Content reviewed according to the LahaLak Quality Charter.Editorial Policy & Medical Standards

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