MSI Immunotherapy Response Test | Lahalak Platform
The key to modern immunotherapy! The MSI test detects DNA repair defects, determining how well colon and endometrial tumors will respond to personalized and effective immunotherapy treatments.
Scientific name: Microsatellite Instability (MSI) Test
The immunohistochemical assay for microsatellite instability (MSI) or loss of mismatch repair (MMR) protein expression aims to evaluate the status of four key proteins in the MMR system (MLH1, MSH2, MSH6, and PMS2) within cancer cell nuclei. It determines whether a tumor exhibits high microsatellite instability (MSI-H), which is associated with los...
Service type
Laboratory test (Tissue)
Duration
10-15 minutes
Fasting
Fasting is not required
Included Services
- Detailed analysis to assess the status of conformation repair proteins (MMR) in tumor tissues
- Consult a pathologist, oncologist, or geneticist to interpret the results.
- Personal support services from Lahalak
Medical Service Information
Conditions & Notices
- Fasting is not required, as the sample is tissue (biopsy or excision).
- The tissue sample must be immediately preserved in 10% standard neutral formalin to ensure the preservation of the integrity of the nuclear antigens.
- This analysis is mandatory for all cases of invasive colorectal cancer, and strongly recommended for endometrial cancer.
- It is usually requested as a set (package) that includes all four proteins together (MLH1, PMS2, MSH2, MSH6).
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