• Which malabsorption conditions might affect Vitamin K1 levels?

Conditions such as cystic fibrosis, biliary liver diseases, and inflammatory bowel diseases (like Crohn's or ulcerative colitis) can impair the absorption of Vitamin K1.

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Vitamin K1 Level Test

Vitamin K1 (Phylloquinone) Test

Measuring Vitamin K1 levels responsible for blood clotting and bone health, essential for those with bone weakness or those taking blood-thinning medications.

Trusted medical contentUpdated: 04-09-2026Views: 21LHL-2653

About this service

A quantitative test that measures the concentration of vitamin K1 (phylloquinone) in blood serum. Vitamin K1 is the primary plant-based form of vitamin K, absorbed from food (especially green leafy vegetables) and dependent on dietary fat for absorption. It acts as an essential cofactor for the enzyme gamma-glutamyl carboxylase, which activates clotting proteins in the liver (factors II, VII, IX, and X) and calcium-regulating proteins in bones (osteocalcin) and blood vessels.

Conditions and notices

8-12 hours fasting

Fasting for 8-12 hours is recommended, along with abstaining from foods rich in vitamin K (such as leafy green vegetables) for 2-3 days before the examination if recommended by the doctor.

Inform the laboratory of all medications, especially anticoagulants (warfarin), antibiotics, and anticonvulsants.

The sample must be drawn carefully to avoid hemolysis, as it may interfere with analytical accuracy.

Frequently Asked Questions

Short answers to the FAQs published with this service.

• Does the Vitamin K1 test require fasting?

Yes, you are required to fast for 8 to 12 hours before providing a blood sample for this test.

• Who are the primary target groups for this test?

The test is primarily for elderly individuals, patients with fat malabsorption (such as liver or pancreas issues), and those on Warfarin with unstable treatment responses.

• How is Vitamin K1 related to bone health?

Vitamin K helps activate osteocalcin, a protein that binds calcium in the bones; therefore, it is used to help assess osteoporosis risks.

• Why is this test used for patients on Warfarin?

Vitamin K1 Level Test

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Conditions and notices

Frequently Asked Questions

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