Lahalak Medical PlatformDifferentiate Care

Medical Laboratories

Precision Metabolic Health Test

Urinary Orotic Acid Test (LC-MS/MS)

Urinary Orotic Acid test to assess carbohydrate and protein metabolism, contributing to early detection of metabolic disorders and ensuring proper body function.

Trusted medical contentUpdated: 25-04-2026Views: 71LHL-600

View service availability

Precision Metabolic Health Test | Urinary Orotic Acid Test (LC-MS/MS)

Home Service Available

Service typeLaboratory test (Urine)

Duration10-15 minutes

Fasting / preparationFasting is not required

Home serviceAvailable

Medical notice: this information is for education and service understanding. It is not a diagnosis or a recommendation for an unnecessary procedure.

About this service

Urinary Orotic Acid by LC-MS/MS is a specialized laboratory test used to determine the levels of orotic acid in urine samples. This test is important for diagnosing certain metabolic disorders, such as uridine monophosphate synthase deficiency, which can lead to elevated levels of orotic acid. The process involves collecting a urine sample, preparing it, and then using liquid chromatography to separate the components, followed by precise measurements using mass spectrometry. This analysis helps assess kidney function and monitors certain health conditions that may affect nucleotide metabolism. Based on the results, doctors can make informed decisions about necessary treatments and interventions.

Purpose Test

Metabolic Disorders: Such as uridine deficiency, which leads to the accumulation of the acid.
Kidney Function Problems: Where acid levels may rise due to the kidneys' reduced ability to excrete it.
Certain Liver Diseases: Where the liver affects the metabolism of nucleotides.
Evaluation of Genetic Disorders: That affect DNA metabolism.
Monitoring Treatment Effectiveness: Related to metabolic or kidney conditions.

Recommended groups

Patients with metabolic disorders: Such as uridine deficiency or hyperammonemia.
Patients with kidney function problems: To help assess the kidneys' ability to excrete waste.
Individuals showing symptoms of liver issues: Such as jaundice or changes in liver function.
People with genetic conditions: That affect DNA or nucleotide metabolism.
Patients undergoing treatment for specific conditions: To monitor the effectiveness of treatments related to metabolic disorders.

Symptoms indicative

Changes in ammonia levels: Such as elevated blood ammonia levels, which may indicate metabolic disorders.
Kidney function changes: Such as swelling, high blood pressure, or increased urination.
Liver issues symptoms: Such as jaundice (yellowing of the skin and eyes), poor appetite, or excessive fatigue.
Growth or developmental problems: Especially in children with genetic disorders.
Acidosis symptoms: Such as headaches, fatigue, or confusion, which may indicate elevated orotic acid levels.

Normal Levels

0.5 to 5.0 mg/24 hours.

What is included?

✓Orotic Acid, Urine, by Liquid Chromatography-Tandem Mass Spectrometry - LC-MS/MS Test
✓The optimal health guidance based on the result.
✓Personal support services from Lahalak

Conditions and notices

Fasting is not required
The terms and conditions announced on the "Lahalak" medical platform apply.
There are no special conditions for the service other than those mentioned.

Frequently Asked Questions

Short answers to the FAQs published with this service.

What is the purpose of the orotic acid test?

It aims to determine the levels of orotic acid in urine to diagnose metabolic disorders and kidney problems.

How is the sample collected?

A urine sample is collected, and a morning sample is often preferred for accuracy.

What techniques are used in the test?

Liquid chromatography with tandem mass spectrometry (LC-MS/MS) is used to ensure precise measurements.

Does the test require any special preparation before sample collection?

Generally, no special preparation is needed, but avoiding certain foods or medications before the test may be recommended.

What is the turnaround time for results?

The time to obtain results typically ranges from several hours to two days, depending on the laboratory.

Are there any health risks during sample collection?

There are no significant risks, but general safety protocols should be followed.

How are the results interpreted?

The results are compared to reference values, and any increases or decreases may indicate a specific health condition.

Service resources and references

References and additional resources

Reference material and files associated with this service when available.

Scientific references

Shi, X., Qiao, H., Wu, J., Di, B., & Wang, Y. (2022). Quantitative determination of urinary orotic acid by LC-MS/MS for the diagnosis of urea cycle disorders.
Fowler, B., & Leonard, J. V. (1997). Orotic acid measurement in urine: Clinical significance and methods including liquid chromatography.
Houten, S. M., & Waterham, H. R. (2010). LC-MS/MS analysis of urinary orotic acid in patients with hereditary orotic aciduria and urea cycle defects.
Erez, A., & Blau, N. (2014). Orotic aciduria and quantitative urinary analysis by LC-MS/MS: Diagnostic applications in inborn errors of metabolism.

Labeeb & Search Tools

Let us help you

Use Labeeb smart tools to understand reports related to (Medical Laboratories), or search the platform directory directly.

Browse services alphabetically A-Z

LahaLak is here to help

Didn’t find the service?

We can help request the service and prepare your inquiry, or you can ask Labeeb to guide you to the most suitable category or service.

Phone call

Your opinion matters

Was this content helpful?

Have a note?

Important Notice:

Content on LahaLak is provided for educational purposes only. It is not a medical diagnosis, prescription, or substitute for consulting a qualified clinician. Medical decisions should not be made from this content alone.

Content reviewed according to the LahaLak Quality Charter.Editorial Policy & Medical Standards

View service availability

View availability

Medical Laboratories

Precision Metabolic Health Test

Urinary Orotic Acid Test (LC-MS/MS)

Urinary Orotic Acid test to assess carbohydrate and protein metabolism, contributing to early detection of metabolic disorders and ensuring proper body function.

Trusted medical contentUpdated: 25-04-2026Views: 71LHL-600

View service availability

Home Service Available

Service typeLaboratory test (Urine)

Duration10-15 minutes

Fasting / preparationFasting is not required

Home serviceAvailable

Medical notice: this information is for education and service understanding. It is not a diagnosis or a recommendation for an unnecessary procedure.

About this service

Purpose Test

Metabolic Disorders: Such as uridine deficiency, which leads to the accumulation of the acid.
Kidney Function Problems: Where acid levels may rise due to the kidneys' reduced ability to excrete it.
Certain Liver Diseases: Where the liver affects the metabolism of nucleotides.
Evaluation of Genetic Disorders: That affect DNA metabolism.
Monitoring Treatment Effectiveness: Related to metabolic or kidney conditions.

Recommended groups

Patients with metabolic disorders: Such as uridine deficiency or hyperammonemia.
Patients with kidney function problems: To help assess the kidneys' ability to excrete waste.
Individuals showing symptoms of liver issues: Such as jaundice or changes in liver function.
People with genetic conditions: That affect DNA or nucleotide metabolism.
Patients undergoing treatment for specific conditions: To monitor the effectiveness of treatments related to metabolic disorders.

Symptoms indicative

Changes in ammonia levels: Such as elevated blood ammonia levels, which may indicate metabolic disorders.
Kidney function changes: Such as swelling, high blood pressure, or increased urination.
Liver issues symptoms: Such as jaundice (yellowing of the skin and eyes), poor appetite, or excessive fatigue.
Growth or developmental problems: Especially in children with genetic disorders.
Acidosis symptoms: Such as headaches, fatigue, or confusion, which may indicate elevated orotic acid levels.

Normal Levels

0.5 to 5.0 mg/24 hours.

What is included?

✓Orotic Acid, Urine, by Liquid Chromatography-Tandem Mass Spectrometry - LC-MS/MS Test
✓The optimal health guidance based on the result.
✓Personal support services from Lahalak

Conditions and notices

Fasting is not required
The terms and conditions announced on the "Lahalak" medical platform apply.
There are no special conditions for the service other than those mentioned.

Frequently Asked Questions

Short answers to the FAQs published with this service.

What is the purpose of the orotic acid test?

It aims to determine the levels of orotic acid in urine to diagnose metabolic disorders and kidney problems.

How is the sample collected?

A urine sample is collected, and a morning sample is often preferred for accuracy.

What techniques are used in the test?

Liquid chromatography with tandem mass spectrometry (LC-MS/MS) is used to ensure precise measurements.

Does the test require any special preparation before sample collection?

Generally, no special preparation is needed, but avoiding certain foods or medications before the test may be recommended.

What is the turnaround time for results?

The time to obtain results typically ranges from several hours to two days, depending on the laboratory.

Are there any health risks during sample collection?

There are no significant risks, but general safety protocols should be followed.

How are the results interpreted?

The results are compared to reference values, and any increases or decreases may indicate a specific health condition.

Service resources and references

References and additional resources

Reference material and files associated with this service when available.

Scientific references

Shi, X., Qiao, H., Wu, J., Di, B., & Wang, Y. (2022). Quantitative determination of urinary orotic acid by LC-MS/MS for the diagnosis of urea cycle disorders.
Fowler, B., & Leonard, J. V. (1997). Orotic acid measurement in urine: Clinical significance and methods including liquid chromatography.
Houten, S. M., & Waterham, H. R. (2010). LC-MS/MS analysis of urinary orotic acid in patients with hereditary orotic aciduria and urea cycle defects.
Erez, A., & Blau, N. (2014). Orotic aciduria and quantitative urinary analysis by LC-MS/MS: Diagnostic applications in inborn errors of metabolism.

Service availability

Choose a provider and branch

Each provider has one service price, then you choose from its available branches.

Labeeb & Search Tools

Let us help you

Use Labeeb smart tools to understand reports related to (Medical Laboratories), or search the platform directory directly.

Browse services alphabetically A-Z

LahaLak is here to help

Didn’t find the service?

We can help request the service and prepare your inquiry, or you can ask Labeeb to guide you to the most suitable category or service.

Phone call

Related services

Services you might also like

Medical service

Klippel-Feil Syndrome Genetic Panel

Discover the genetic causes of cervical vertebral fusion with a precise NGS panel for Klippel-Feil syndrome, enabling early diagnosis and a comprehensive treatment plan to support spinal health and mobility.

Starting from5,229.05 SAR

View service

Medical service

TCOF1 Gene Sequencing Test

This comprehensive DNA sequencing test analyzes the TCOF1 gene to identify mutations associated with Treacher Collins syndrome, providing essential data for clinical diagnosis and informed family planning.

Starting from11,550 SAR

View service

Medical service

Discover Your MODY Genetic Type

A precise genetic test that helps diagnose hereditary forms of diabetes caused by specific gene mutations, enabling the determination of the most effective personalized treatment plan for your condition.

Starting from12,650 SAR

View service

Medical service

Alstrom Syndrome Genetic Screening

A specialized genetic test designed to identify copy-number variations in the ALMS1 gene, facilitating early diagnosis and personalized management for individuals with suspected Alstrom syndrome.

Starting from15,070 SAR

View service

Your opinion matters

Was this content helpful?

Have a note?

Important Notice:

Content reviewed according to the LahaLak Quality Charter.Editorial Policy & Medical Standards

View service availability