• Does this laboratory test require fasting?

No, there is no requirement to fast before having the SHBG blood test.

• How does the SHBG test help in evaluating biologically active hormones?

Measuring SHBG levels allows for the calculation of 'free' or biologically active hormones, such as free testosterone, by combining SHBG results with total hormone measurements.

Medical Laboratories

Sex Hormone-Binding Globulin Test

Sex Hormone-Binding Globulin (SHBG) Test

Essential analysis to evaluate the balance of active sex hormones, aiding in diagnosing fertility issues, hair loss, and libido disorders for both men and women.

Trusted medical contentUpdated: 04-09-2026Views: 39LHL-2589

About this service

This analysis measures the concentration of sex hormone-binding globulin (SHBG), a protein produced by the liver that binds strongly to testosterone and estradiol (estrogen), regulating their "free" and biologically active amounts in the blood. SHBG levels directly affect the balance between male and female hormones and their availability to tissues.

Conditions and notices

Fasting is not required

Fasting is not usually required, but it is preferable to draw the sample in the morning (between 8-10 am) when hormone levels are at their peak.

For women of reproductive age, the day of the menstrual cycle should be stated accurately, as the timing affects the results (often requested on days 2-5 of the cycle).

Inform your doctor about all medications and supplements.

Frequently Asked Questions

Short answers to the FAQs published with this service.

• What does the SHBG test measure?

This test measures the concentration of Sex Hormone-Binding Globulin, a liver-produced protein that binds to testosterone and estradiol to regulate their active levels in the blood.

• When is this test recommended for women?

It is recommended for women showing signs of excess androgens, such as hirsutism (excess body hair), male-pattern hair loss, severe acne, or irregular menstrual cycles.

• Why might a man need an SHBG test?

Men may need this test to evaluate symptoms of low testosterone, such as decreased libido, fatigue, erectile dysfunction, or reduced muscle mass.

• Can SHBG levels be affected by other health conditions?

Sex Hormone-Binding Globulin Test

About this service

What is included?

Conditions and notices

Frequently Asked Questions

Choose a provider and branch

Let us help you

Didn’t find the service?

Services you might also like

Prolactin (Milk Hormone) Test

Check Your Ovarian Reserve

Key to Fertility and Balance

Luteinizing Hormone (LH) Test

Your opinion matters

Was this content helpful?

Have a note?