Lahalak Medical PlatformDifferentiate Care

Medical Laboratories

PML-RAR Alpha Genetic Test

An advanced genetic test to detect mutations linked to acute promyelocytic leukemia, supporting early diagnosis and rapid therapeutic intervention for optimal health outcomes.

Trusted medical contentUpdated: 25-04-2026Views: 41LHL-639

View service availability

PML-RAR Alpha Genetic Test | PML-RAR Alpha Genetic Test

Home Service Available

Service typeGenetic test (Blood)

Duration10-15 minutes

Fasting / preparationFasting is not required

Home serviceAvailable

Medical notice: this information is for education and service understanding. It is not a diagnosis or a recommendation for an unnecessary procedure.

About this service

PML-RAR Alpha analysis is a laboratory test used to detect genetic changes associated with acute promyelocytic leukemia (APL). This test is linked to the presence of the PML-RAR alpha gene, which results from the fusion of two different genes, leading to alterations in cell growth. It is an important tool for diagnosing the disease, helping physicians accurately determine the condition and assess the patient’s response to treatment. The sample is usually collected from blood or bone marrow and analyzed using advanced techniques such as polymerase chain reaction (PCR). The results of this test contribute to developing an appropriate treatment plan and help monitor the progression of the health condition.

Purpose Test

Diagnosing Acute Promyelocytic Leukemia (APL): The presence of this genetic alteration is a hallmark of this type of leukemia.
Assessing Disease Progression: It helps evaluate the severity of the disease and how much it has spread.
Monitoring Treatment Response: The test is used to track how well the patient is responding to targeted therapies.
Early Diagnosis: It contributes to the early and accurate diagnosis of APL, allowing for timely treatment.
Monitoring Treatment Effectiveness: It helps determine if the treatment is effective, especially with therapies like all-trans retinoic acid (ATRA) and arsenic trioxide (ATO).

Recommended groups

Patients with Acute Promyelocytic Leukemia (APL): Those showing symptoms that suggest this type of leukemia.
Individuals with Unexplained Signs or Symptoms Related to Blood Disorders: For example, easy bruising or excessive bleeding.
Patients Previously Diagnosed with Other Blood Disorders: Those who need further evaluation or clarification regarding their condition.
Patients Undergoing Chemotherapy or Targeted Therapy for Leukemia: To monitor the response to treatment.

Symptoms indicative

Signs of Leukemia: Such as severe fatigue, unexplained weight loss, fever, and night sweats, which may suggest blood disorders.
Bruising and Bleeding: Unexplained bruising or excessive bleeding, such as frequent nosebleeds or gum bleeding, which could indicate platelet problems or the body's response to medications.
Changes in Blood Cell Counts: Such as an unexplained decrease in white or red blood cells, which may require further evaluation.
Symptoms of Bone Marrow Failure: Such as general weakness, dizziness, or difficulty breathing, which are signs of compromised blood cell production.
Family History: A family history of blood cancers or leukemia may prompt this test as part of a comprehensive evaluation.

Normal Levels

Negative result: Indicates the absence of the gene, suggesting that the specific type of leukemia is not present.
Positive result: Indicates the presence of the gene, which requires further testing and medical evaluation to confirm the diagnosis.

What is included?

✓PML-RAR Alpha Test
✓The optimal health guidance based on the result.
✓Personal support services from Lahalak

Conditions and notices

Fasting is not required
The terms and conditions announced on the "Lahalak" medical platform apply.
There are no special conditions for the service other than those mentioned.

Frequently Asked Questions

Short answers to the FAQs published with this service.

What is the PML-RAR Alpha test?

The PML-RAR Alpha test is used to detect the presence of the PML-RAR Alpha gene, which is associated with certain types of leukemia, such as acute promyelocytic leukemia (APL).

How is the test performed?

A sample of blood or bone marrow is collected and then sent to a laboratory for analysis.

Is any special preparation required before the test?

Typically, no special preparation is required for the test. However, it's best to consult with your doctor to confirm.

What are the expected results?

Positive results indicate the presence of the gene, which would require further testing to confirm the diagnosis.

What are the risks associated with the test?

The risks are minimal and primarily involve discomfort or bruising at the site where the sample is drawn.

What do abnormal results mean?

Abnormal results suggest the possibility of blood disorders, and may require additional tests or medical evaluation.

How long does it take to get results?

Results usually take a few days, but the timeframe can vary depending on the laboratory.

Service resources and references

References and additional resources

Reference material and files associated with this service when available.

Scientific references

Lo‑Coco, F., Diverio, D., & Mandelli, F. (1995). The PML/RAR alpha fusion gene in the diagnosis and monitoring of acute promyelocytic leukemia. Haematologica.
Lansdorp, P. M., & Baer, M. R. (1993). Diagnosis of acute promyelocytic leukaemia by RT‑PCR: detection of PML‑RAR alpha and RAR alpha‑PML fusion transcripts. Blood.
Grimwade, D., Walker, H., & Oliver, A. J. (1993). Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for the PML/RAR‑alpha fusion mRNA. Blood.
Lo‑Coco, F., & Mandelli, F. (2001). The PML‑RAR alpha transcript in long‑term follow‑up of acute promyelocytic leukemia patients. Haematologica.

Labeeb & Search Tools

Let us help you

Use Labeeb smart tools to understand reports related to (Medical Laboratories), or search the platform directory directly.

Browse services alphabetically A-Z

LahaLak is here to help

Didn’t find the service?

We can help request the service and prepare your inquiry, or you can ask Labeeb to guide you to the most suitable category or service.

Phone call

Your opinion matters

Was this content helpful?

Have a note?

Important Notice:

Content on LahaLak is provided for educational purposes only. It is not a medical diagnosis, prescription, or substitute for consulting a qualified clinician. Medical decisions should not be made from this content alone.

Content reviewed according to the LahaLak Quality Charter.Editorial Policy & Medical Standards

View service availability

View availability

Medical Laboratories

PML-RAR Alpha Genetic Test

An advanced genetic test to detect mutations linked to acute promyelocytic leukemia, supporting early diagnosis and rapid therapeutic intervention for optimal health outcomes.

Trusted medical contentUpdated: 25-04-2026Views: 41LHL-639

View service availability

Home Service Available

Service typeGenetic test (Blood)

Duration10-15 minutes

Fasting / preparationFasting is not required

Home serviceAvailable

Medical notice: this information is for education and service understanding. It is not a diagnosis or a recommendation for an unnecessary procedure.

About this service

Purpose Test

Diagnosing Acute Promyelocytic Leukemia (APL): The presence of this genetic alteration is a hallmark of this type of leukemia.
Assessing Disease Progression: It helps evaluate the severity of the disease and how much it has spread.
Monitoring Treatment Response: The test is used to track how well the patient is responding to targeted therapies.
Early Diagnosis: It contributes to the early and accurate diagnosis of APL, allowing for timely treatment.
Monitoring Treatment Effectiveness: It helps determine if the treatment is effective, especially with therapies like all-trans retinoic acid (ATRA) and arsenic trioxide (ATO).

Recommended groups

Patients with Acute Promyelocytic Leukemia (APL): Those showing symptoms that suggest this type of leukemia.
Individuals with Unexplained Signs or Symptoms Related to Blood Disorders: For example, easy bruising or excessive bleeding.
Patients Previously Diagnosed with Other Blood Disorders: Those who need further evaluation or clarification regarding their condition.
Patients Undergoing Chemotherapy or Targeted Therapy for Leukemia: To monitor the response to treatment.

Symptoms indicative

Signs of Leukemia: Such as severe fatigue, unexplained weight loss, fever, and night sweats, which may suggest blood disorders.
Bruising and Bleeding: Unexplained bruising or excessive bleeding, such as frequent nosebleeds or gum bleeding, which could indicate platelet problems or the body's response to medications.
Changes in Blood Cell Counts: Such as an unexplained decrease in white or red blood cells, which may require further evaluation.
Symptoms of Bone Marrow Failure: Such as general weakness, dizziness, or difficulty breathing, which are signs of compromised blood cell production.
Family History: A family history of blood cancers or leukemia may prompt this test as part of a comprehensive evaluation.

Normal Levels

Negative result: Indicates the absence of the gene, suggesting that the specific type of leukemia is not present.
Positive result: Indicates the presence of the gene, which requires further testing and medical evaluation to confirm the diagnosis.

What is included?

✓PML-RAR Alpha Test
✓The optimal health guidance based on the result.
✓Personal support services from Lahalak

Conditions and notices

Fasting is not required
The terms and conditions announced on the "Lahalak" medical platform apply.
There are no special conditions for the service other than those mentioned.

Frequently Asked Questions

Short answers to the FAQs published with this service.

What is the PML-RAR Alpha test?

The PML-RAR Alpha test is used to detect the presence of the PML-RAR Alpha gene, which is associated with certain types of leukemia, such as acute promyelocytic leukemia (APL).

How is the test performed?

A sample of blood or bone marrow is collected and then sent to a laboratory for analysis.

Is any special preparation required before the test?

Typically, no special preparation is required for the test. However, it's best to consult with your doctor to confirm.

What are the expected results?

Positive results indicate the presence of the gene, which would require further testing to confirm the diagnosis.

What are the risks associated with the test?

The risks are minimal and primarily involve discomfort or bruising at the site where the sample is drawn.

What do abnormal results mean?

Abnormal results suggest the possibility of blood disorders, and may require additional tests or medical evaluation.

How long does it take to get results?

Results usually take a few days, but the timeframe can vary depending on the laboratory.

Service resources and references

References and additional resources

Reference material and files associated with this service when available.

Scientific references

Lo‑Coco, F., Diverio, D., & Mandelli, F. (1995). The PML/RAR alpha fusion gene in the diagnosis and monitoring of acute promyelocytic leukemia. Haematologica.
Lansdorp, P. M., & Baer, M. R. (1993). Diagnosis of acute promyelocytic leukaemia by RT‑PCR: detection of PML‑RAR alpha and RAR alpha‑PML fusion transcripts. Blood.
Grimwade, D., Walker, H., & Oliver, A. J. (1993). Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for the PML/RAR‑alpha fusion mRNA. Blood.
Lo‑Coco, F., & Mandelli, F. (2001). The PML‑RAR alpha transcript in long‑term follow‑up of acute promyelocytic leukemia patients. Haematologica.

Service availability

Choose a provider and branch

Each provider has one service price, then you choose from its available branches.

Labeeb & Search Tools

Let us help you

Use Labeeb smart tools to understand reports related to (Medical Laboratories), or search the platform directory directly.

Browse services alphabetically A-Z

LahaLak is here to help

Didn’t find the service?

We can help request the service and prepare your inquiry, or you can ask Labeeb to guide you to the most suitable category or service.

Phone call

Related services

Services you might also like

Medical service

Newborn Screening - Type 2

An expanded screening panel for newborns aimed at discovering a wide range of rare genetic and metabolic diseases, providing the highest level of health safety for your baby.

Starting from312.5 SAR

View service

Medical service

Thymine Test for DNA Health

Advanced test measuring Thymine, a key DNA base, to accurately detect genetic disorders and metabolic imbalances using sophisticated GC-MS technology for precise results.

Starting from218.75 SAR

View service

Medical service

Identify Albinism Genetic Causes

A comprehensive genetic panel analyzing genes linked to oculocutaneous and ocular albinism, identifying specific mutations to support clinical diagnosis and inform future healthcare decisions for families.

Starting from17,790.3 SAR

View service

Medical service

Non-Invasive Prenatal Test (NIPT)

A safe and highly accurate blood test to screen for fetal genetic abnormalities early in pregnancy, providing peace of mind for expecting parents from home.

Starting from1,437.5 SAR

View service

Your opinion matters

Was this content helpful?

Have a note?

Important Notice:

Content reviewed according to the LahaLak Quality Charter.Editorial Policy & Medical Standards

View service availability