DHR Immune Function Test | Lahalak Medical Platform

A specialized test to evaluate white blood cell ability to fight infection, essential for accurately diagnosing genetic immune disorders and determining the right treatment.

Scientific name: Dihydrorhodamine (DHR) Test

The Dihydrorhodamine (DHR) test is a specialized test used to assess the function of white blood cells, particularly neutrophils, in producing reactive oxygen species (ROS) essential for fighting infections. This test is a crucial tool for diagnosing immune disorders such as Chronic Granulomatous Disease (CGD). The test is conducted using flow cyto...

Dihydrorhodamine (DHR) Test - Immune Efficiency Test
Service type Laboratory Test
Duration 10-15 minutes
Fasting Fasting is not required

Included Services

  • Dihydrorhodamine (DHR) test analysis
  • The optimal health guidance based on the result.
  • Personal support services from Lahalak

Medical Service Information

Test purpose

  • Immune dysfunction: It evaluates the ability of white blood cells, specifically neutrophils, to produce reactive oxygen species (ROS) used to fight infections.
  • Diagnosis of Chronic Granulomatous Disease (CGD): A genetic disorder that impairs the ability of immune cells to effectively kill bacteria and fungi.
  • Detection of functional defects in the NADPH Oxidase enzyme: The enzyme responsible for producing ROS in neutrophils.
  • Assessment of immune system efficiency in patients with recurrent or unexplained infections.

Recommended groups

  • Individuals with recurrent and unexplained infections: Chronic bacterial or fungal infections. Difficulty recovering from severe infections.
  • Chronic bacterial or fungal infections.
  • Difficulty recovering from severe infections.
  • Children and adolescents suspected of having genetic immune disorders: Especially in cases with a family history of Chronic Granulomatous Disease (CGD).
  • Especially in cases with a family history of Chronic Granulomatous Disease (CGD).
  • Individuals with clear immune system deficiencies: Symptoms may include recurrent abscesses, pneumonia, or bone infections.

Indicative symptoms

  • Recurrent or chronic infections: Frequent bacterial or fungal infections in the respiratory system, skin, bones, or gastrointestinal tract.
  • Frequent bacterial or fungal infections in the respiratory system, skin, bones, or gastrointestinal tract.
  • Recurrent abscess formation: Abscesses in the skin or internal organs (e.g., liver, lungs).
  • Abscesses in the skin or internal organs (e.g., liver, lungs).
  • Severe pneumonia: Recurrent pneumonia or infections that do not respond well to treatment.
  • Recurrent pneumonia or infections that do not respond well to treatment.

FAQ

  • What is the DHR test? The DHR test is an assessment of the function of white blood cells (neutrophils) in producing reactive oxygen species (ROS) necessary for fighting infections.
  • Why is this test requested? It is requested to evaluate immune system efficiency and diagnose disorders such as Chronic Granulomatous Disease (CGD) in patients with recurrent or chronic infections.
  • How is the test performed? A small blood sample is taken from the patient and analyzed using flow cytometry after adding DHR substance.
  • Does the test require any preparation? Typically, no fasting or special preparations are needed unless otherwise instructed by the doctor.
  • Is the test painful? The blood collection is done using the standard procedure for blood draws, which is relatively simple and not painful.
  • How long does it take to get the results? The time varies depending on the lab, but results are usually available within 1 to 3 business days.

Normal levels

  • Normal Response: Indicates that neutrophils are able to produce reactive oxygen species (ROS) sufficiently, meaning there is no dysfunction in their activity.
  • Indicates that neutrophils are able to produce reactive oxygen species (ROS) sufficiently, meaning there is no dysfunction in their activity.
  • Low or Absent Response: Suggests a dysfunction in ROS production, which may indicate a disorder such as Chronic Granulomatous Disease (CGD).
  • Suggests a dysfunction in ROS production, which may indicate a disorder such as Chronic Granulomatous Disease (CGD).
  • The fluorescence level produced by the DHR substance in the cells is compared to the reference level in the testing laboratory.
  • Values may vary depending on age and gender, but the laboratory technician will provide a precise evaluation based on the reference group used in the lab.

Conditions & Notices

  • The terms and conditions announced on the "Lahalak" medical platform apply.
  • There are no special conditions for the service other than those mentioned.

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