Comprehensive Renal Biopsy - Renal Biopsy: Electron and Immunofluorescence Microscopy

This is a comprehensive diagnostic procedure in which a detailed kidney tissue sample is examined using three microscopic techniques: 1) Light microscopy (LM): to assess the histological structure and glomerulonephritis. 2) Immunohistochemistry (IF): to detect the deposition of antibodies or complement (IgG, IgA, IgM, C3) in the renal glomeruli. 3) Electron microscopy (EM): to evaluate subtle changes in the layers of the glomerular basement membrane and the location of dense electron deposits. This integration is essential for the definitive diagnosis of glomerular nephritis.