Guide to Lung and Kidney Tumors - Napsin A Immunohistochemistry Test

The immunohistochemical assay for NAPSIN A (Aspartic Peptidase of the Pepsin Family A) aims to detect this protease enzyme, which is primarily expressed in type II alveolar cells of the lung and in the epithelial cells of the proximal tubules of the kidney. It is considered a highly sensitive and specific marker for lung adenocarcinoma and renal cell carcinoma (clear cell type).