Cell Lysis Protection Guard - Lymphocyte CD59 (Protectin) Surface Marker Test

Flow cytometry is used to assess the expression of CD59 protein (also known as Protectin or MAC-IP) on the surface of lymphocytes and blood cells. CD59 acts as a final inhibitor of the complement system's membrane attack complex (MAC), preventing cell lysis. Its measurement is essential for the diagnosis of paroxysmal nocturnal hemolytic anemia (PNH).