This laboratory test, which falls under the category of antiphospholipid antibodies, is performed on blood plasma. It measures the presence and effect of a type of autoantibody (IgG, IgM, or both) that interferes with phospholipid-dependent coagulation reactions in the laboratory, leading to prolonged clotting time in certain tests. Despite its name, it is associated with an increased risk of clotting (not bleeding) in the body.