CD23 Chronic Leukemia Test - Immunohistochemistry (IHC) for CD23

Immunohistochemistry for CD23 detects the expression of CD23 protein (FcεRII), a low-affinity receptor for Immunoglobulin E. It is a particularly useful marker in diagnosing B-cell Chronic Lymphocytic Leukemia (B-CLL) and differentiating it from other B-cell lymphomas. It is also expressed on activated B-cells and some follicular dendritic cells.