Question 1

Purpose of the Procedure

Accepted Answer

Detect large deletions and duplications in BRCA1 and BRCA2 genes. Assess hereditary risks for breast, ovarian, and related cancers. Provide critical genetic insights for family members regarding inherited risks.

Question 2

Target Groups

Accepted Answer

Individuals with a strong family history of breast or ovarian cancer. Patients with negative standard sequencing results but strong clinical suspicion. Anyone seeking a comprehensive assessment of genetic cancer predispositions.

Question 3

Why MLPA Technology?

Accepted Answer

It identifies 'Large Genomic Rearrangements' missed by standard sequencing methods. Gold standard for diagnosing copy number variations in genetic testing. Enables personalized preventive or therapeutic planning based on specific genetic findings.

Precise Hereditary Cancer Risk Screening - BRCA1/2 Deletion and Duplication Analysis (MLPA)