β-Catenin IHC Test for Tumor Mutations | Lahalak
Beta-catenin analysis to detect genetic defects in cell pathways, aiding in the diagnosis of fibroblastomas and pediatric liver tumors with molecular precision.
Scientific name: Immunohistochemistry: β-Catenin
Immunohistochemical assay (IHC) assesses the expression pattern and intracellular localization of the protein β-catenin. Normally, β-catenin is found in the cell membrane (associated with icadaherin) and in the cytoplasm. In cases of activating mutations in the CTNNB1 gene (which encodes β-catenin) or in the Wnt pathway, the protein accumulates in...
Service type
Laboratory test (Tissue Biopsy)
Duration
10-15 minutes
Fasting
Fasting is not required
Included Services
- A detailed analysis to assess the expression pattern and localization of beta-catenin protein in tissue samples.
- Consult a pathologist specializing in soft tissue or liver tumors to interpret the results.
- Personal support services from Halak.
Medical Service Information
Conditions & Notices
- The analysis does not require the patient to fast, as it is performed on a fixed tissue sample.
- The need for a sufficient tissue sample of the suspected tumor.
- It is commonly requested as part of a diagnostic package: when fibroblastoma is suspected, it is usually requested as part of a diagnostic panel that includes β-Catenin, SMA, Desmin, and S100. For liver tumors, it is part of a liver marker panel.