P16 IHC HPV Infection Test | Lahalak Platform
Essential screening to detect cancerous changes associated with Human Papillomavirus (HPV), contributing to the prevention and early diagnosis of cervical cancer as well as head and neck tumors.
Scientific name: Immunohistochemistry (IHC) for P16
Immunohistochemical assay for p16 (CDKN2A) aims to detect overexpression of this cell cycle inhibitor. This overexpression is an indirect marker of disruption of the pRb pathway by the E7 protein of high-risk human papillomavirus (HPV). P16 is primarily used as a surrogate marker for HPV infection in cervical cancers and oropharyngeal head and neck...
Service type
Laboratory test (Tissue)
Duration
10-15 minutes
Fasting
Fasting is not required
Included Services
- Detailed analysis to detect overexpression of the P16 protein in tissue samples
- Consult a pathologist or gynecologist to interpret the results.
- Personal support services from Lahalak
Medical Service Information
Conditions & Notices
- Fasting is not required, as the sample is a tissue sample (biopsy).
- The biopsy sample must be immediately preserved in 10% formalin.
- In cervical biopsies, P16 is routinely requested in cases of CIN2 or when there is uncertainty in the classification of the degree of dysplasia.
- In head and neck cancers, all cases of squamous cell carcinoma of the tonsils and base of the tongue are required for predictive classification.
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