DOG-1 IHC Test for GIST Tumors | Lahalak Platform
A vital and sensitive test for diagnosing Gastrointestinal Stromal Tumors (GIST), helping guide patients toward highly effective targeted therapies.
Scientific name: Immunohistochemistry: DOG-1
Immunohistochemistry for DOG-1 (Discovered On GIST-1) aims to detect the DOG-1 protein (also known as ANO1), a calcium-activated chloride channel. Its expression is a highly sensitive and specific marker for Gastrointestinal Stromal Tumors (GISTs), and it is often positive even in PDGFRA-mutated GISTs or those that are negative for CD117 (KIT).
Service type
Histopathology Laboratory Test
Duration
30-45 minutes
Fasting
Fasting is not required
Included Services
- Detailed analysis for DOG-1 protein in tissue samples
- Consultation on interpreting results with a pathologist
- Personal support services from Lehlek
Medical Service Information
Conditions & Notices
- Fasting is not required, as the sample is histological (biopsy or surgical resection).
- The histological sample must be preserved immediately in 10% formalin.
- This test is routinely ordered with CD117 (KIT) as part of the standard package for the diagnosis of gastrointestinal spindle cell tumors.
- Please provide information on the exact location of the tumor (stomach, small intestine, etc.).
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