• Can HOMA-IR help predict diabetes risk?

Yes, it allows for early detection of Type 2 diabetes risk even before a significant rise in fasting blood sugar occurs.

• Who is the HOMA-IR test recommended for?

The test is recommended for individuals with abdominal obesity, a family history of diabetes, or prediabetes. It is also used for those with non-alcoholic fatty liver disease (NAFLD), hypertension, or dyslipidemia associated with metabolic syndrome.

Medical Laboratories

Insulin Resistance (HOMA-IR) Test

HOMA-IR (Insulin Resistance) Test

Concerned about diabetes? This analysis measures how well your cells respond to insulin, helping detect diabetes and heart disease risks early, allowing for a personalized prevention plan.

Trusted medical contentUpdated: 04-09-2026Views: 141LHL-3133

About this service

The HOMA-IR (Hotline-Assessed Insulin Resistance Rating Scale) is a mathematical index derived from two values: fasting plasma glucose (FPG) and fasting plasma insulin. It is calculated using the formula: (Fasting glucose (mg/dL) × Fasting insulin (µU/mL)) / 405. This index reflects the degree of insulin resistance in the liver and peripheral tissues. The higher the HOMA-IR value, the greater the cellular resistance to insulin, meaning the body needs to produce more insulin to maintain normal blood sugar levels.

Conditions and notices

8-12 hours fasting

Fasting for 8-12 hours is required before the sample is taken (no food or drink except water). This is essential for accurate measurement of fasting glucose and insulin.

You should inform your doctor about all medications you are taking, especially those that affect blood sugar (such as metformin, insulin) and corticosteroids. Your doctor may ask you to stop taking some of them before the examination.

It is advised to avoid strenuous exercise for 24 hours before the test, as it may temporarily lower insulin and glucose levels.

Frequently Asked Questions

Short answers to the FAQs published with this service.

• What is the HOMA-IR index?

The HOMA-IR is a calculated indicator derived from fasting plasma glucose and insulin levels to quantify insulin resistance.

• What are the fasting requirements for this test?

Patients are required to fast for 8 to 12 hours before the blood sample is taken.

• How is HOMA-IR used in managing PCOS?

It assesses the severity of insulin resistance in women with Polycystic Ovary Syndrome, where it is a core component of the condition.

• Which skin condition might indicate a need for this test?

Insulin Resistance (HOMA-IR) Test

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Conditions and notices

Frequently Asked Questions

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