Hep Par-1 IHC Test for Liver Tumors | Lahalak Platform
A reliable test to confirm the hepatic origin of cancer cells, aiding in diagnosing primary liver cancer and accurately distinguishing it from metastases.
Scientific name: Hep Par-1 Immunohistochemistry Test
Immunohistochemical testing for Hep Par-1 (Hepatocyte Paraffin 1) aims to detect an antigen present in the mitochondria of both normal and cancerous liver cells (hepatocytes). It is a highly sensitive and specific marker of hepatocyte origin, making it an essential tool in confirming the diagnosis of hepatocellular carcinoma (HCC) and differentiati...
Service type
Histopathology Laboratory Test
Duration
30-45 minutes
Fasting
Fasting is not required
Included Services
- There are no numerical values. The histological expression is read qualitatively, focusing on the distinctive coloring pattern:
- Positive (typical hepatocyte pattern): Strong and intense cytoplasmic granular (metallic) staining in normal or tumor hepatocytes. The granules represent mitochondria. The staining is often heterogeneous (strongest at the cell margin or around the nucleus).
- Negative: Absence of characteristic granular coloring. There may be non-specific background coloring.
- personal support services from Lahalak
Medical Service Information
Conditions & Notices
- Fasting is not required, as the sample is tissue-based (liver biopsy or from a metastatic site).
- The biopsy sample must be immediately preserved in 10% formalin.
- This analysis is requested almost routinely in liver biopsies suspected of containing a tumor.
- It is often requested as part of a comprehensive liver tumor package that also includes Arginase-1, Glypican-3, CD10, and CK7.
Medical services you might also like
