How long does it take to get results?

Results typically appear within one to two weeks, depending on the laboratory.

What are the risks associated with the test?

Risks are minimal, including discomfort during the blood draw or minor bruising.

What do the test results mean?

Positive results indicate the presence of mutations associated with FMF, while negative results may require additional evaluations.

Medical Laboratories

FMF 12-Mutation Genetic Test

Familial Mediterranean Fever (FMF) 12-Mutation Test

Advanced genetic screening for 12 mutations causing Familial Mediterranean Fever, enabling precise diagnosis and effective management of recurrent pain and inflammatory episodes.

Trusted medical contentUpdated: 25-04-2026Views: 85LHL-383

About this service

The Familial Mediterranean Fever (FMF) 12 Mutation test is a genetic test used to identify mutations associated with Familial Mediterranean Fever, a hereditary disorder that primarily affects individuals of Mediterranean descent. The main symptoms of the disease include recurrent episodes of fever, abdominal pain, and arthritis. This test is performed when FMF is suspected, especially in individuals with a family history of the disease or those exhibiting similar symptoms. The test helps identify known genetic mutations, such as those in the MEFV gene, facilitating diagnosis and guiding appropriate treatment. This test is an important tool for understanding genetic risks and providing proper medical support to affected families.

Purpose Test

Genetic Mutations: Identifies known mutations in the MEFV gene, including multiple mutations that can lead to the disease.
FMF Diagnosis: Helps confirm the diagnosis in individuals experiencing recurrent symptoms such as fever and abdominal pain.
Genetic Risk Assessment: Assists families in understanding the likelihood of passing the disease to future generations.
Treatment Guidance: Provides information to help doctors develop an appropriate treatment plan for patients based on the detected mutations.

Recommended groups

Individuals Showing FMF Symptoms: Such as recurrent fever attacks, abdominal pain, arthritis, or skin rash.
People with a Family History: Those with relatives affected by Familial Mediterranean Fever, increasing their risk.
Individuals of Mediterranean Descent: Such as Turks, Arabs, Sephardic Jews, or Armenians, as the disease is more common in these populations.
Patients Diagnosed with Chronic Inflammatory Diseases: To help determine if symptoms are caused by FMF.
Individuals Needing Genetic Assessment: As part of genetic counseling or before pregnancy to understand potential risks.

Symptoms indicative

Recurrent Fever Attacks: Sudden and periodic increases in body temperature.
Severe Abdominal Pain: Resembling colic or cramps, usually recurrent.
Arthritis: Swelling and pain in the joints, especially knees and ankles.
Skin Rash: Such as vasculitic rash that may appear during attacks.
Other Inflammatory Symptoms: Such as lung inflammation or soft tissue inflammation.
Family History of the Disease: Presence of family members affected by FMF or similar symptoms.

Normal Levels

Positive Results: Indicate the presence of a specific mutation associated with the disease, meaning the person may be affected or at risk of developing Familial Mediterranean Fever.
Negative Results: Mean that no known mutations were detected, but this does not rule out other conditions or unknown mutations.

Frequently Asked Questions

Short answers to the FAQs published with this service.

What is the FMF Test?

It is a genetic test used to identify mutations associated with Familial Mediterranean Fever.

Why is this test performed?

To confirm FMF diagnosis when specific symptoms or a family history of the disease are present.

How is the test performed?

A blood sample is drawn and analyzed in the laboratory for genetic mutations in the MEFV gene.

Does the test require any special preparations?

Usually, no preparations are needed, but it is recommended to consult the doctor regarding any medications taken.

FMF 12-Mutation Genetic Test

About this service

Purpose Test

Recommended groups

Symptoms indicative

Normal Levels

What is included?

Conditions and notices

Frequently Asked Questions

References and additional resources

Scientific references

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