Anti-Smith (Sm) Antibody Test | Lahalak Medical Platform

This test is one of the most accurate for confirming systemic lupus erythematosus (SLE), featuring high specificity that helps finalize the diagnosis in complex cases and initiate correct treatment.

Scientific name: Anti-Smith (Sm) Antibody Test

A serological test to detect autoantibodies directed against Smith protein (Sm) antigens, which are small RNA-linked nuclear proteins (snRNPs). These antibodies are highly specific for systemic lupus erythematosus (SLE), with a specificity of >99%. They are present in approximately 10–30% of SLE patients and are often associated with more active di...

Anti-Smith (Sm) Antibody Test - Confirmatory Lupus (Sm) Test
Service type Laboratory test (Blood)
Duration 10-15 minutes
Fasting Fasting is not required

Included Services

  • Analysis to detect Anti-Smith (Anti-Sm) antibodies in blood serum.
  • Consult a rheumatologist to interpret the results.
  • Personal support services from Halak.

Medical Service Information

Conditions & Notices

  • Fasting is not required for the test.
  • It is often requested as part of an extractable antinuclear antibody panel (ENA Panel) following a positive ANA test result.
  • A positive result is considered to have very high diagnostic value.

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