Question 1

Purpose of the Assay

Accepted Answer

Determine the likelihood of breast cancer recurrence within 10 years. Predict whether chemotherapy will be beneficial for the patient. Enable a personalized treatment plan based on the tumor's genetic profile.

Question 2

Target Groups

Accepted Answer

Patients diagnosed with early-stage breast cancer (Stage I or II). Hormone receptor-positive (HR+) tumor cases. HER2-negative breast cancer cases.

Question 3

Understanding the Results

Accepted Answer

Low Recurrence Score (0-25): Low risk of return; chemotherapy benefit is usually minimal. High Recurrence Score (26-100): Higher risk of return; chemotherapy is likely to be beneficial.

Precision Treatment for Breast Cancer - Oncotype DX Breast Cancer Assay