Newborn 17-OHP Screening - Newborn 17-Hydroxyprogesterone (17-OHP) Screening

A newborn screening test measures the blood level of 17-hydroxyprogesterone (17-OHP), the primary hormone that accumulates in the blood when there is a deficiency of the enzyme 21-hydroxylase. This deficiency is the most common cause (over 90%) of congenital adrenal hyperplasia (CAH), a genetic disorder that affects the production of the hormones cortisol and aldosterone.