This intensive interpretive consultation package is based on the review and analysis of immunohistochemical (IHC) test results for two specific markers chosen for a specific clinical or diagnostic reason. The package includes assessing the pattern and intensity of expression of each marker individually, followed by an analysis of the relationship between them (e.g., co-expression, mutual exclusion, or non-correlation). The interpretation is provided by a pathologist to answer a specific clinical question, such as confirming a diagnosis, differentiating between two subtypes, or predicting the response to a particular treatment based on the combined status of the two markers.