A top-tier predictive and innovative consulting package that integrates advanced immunopathology and computational systems biology modeling. It includes detailed analysis of sixteen selected immunohistochemical (IHC) markers to represent a complex network of interconnected pathways within the tumor and its microenvironment. Nonlinear interactions between these pathways are analyzed using advanced analytical tools to generate a predictive model of tumor behavior. The model is reviewed by a team of translational pathologists, clinical bioinformaticians, and oncologists, with the goal of generating data-driven, algorithmic treatment strategies.