Desmin Test for Muscle Tumors - Immunohistochemistry: Desmin

Immunohistochemistry for Desmin aims to detect this intermediate filament protein, a major component of muscle fibers. Desmin is a highly specific marker for muscle differentiation, being expressed in smooth muscle, skeletal muscle, cardiac muscle, and in tumors derived from these tissues (e.g., leiomyoma, rhabdomyosarcoma).