Blood and Tissue Tumor Diagnosis - Immunohistochemistry: CD45 Diagnostic Package

This diagnostic package, based on immunohistochemistry, involves testing for a range of key markers to differentiate between tumor proliferations in tissues. The package primarily includes testing for CD45 (LCA - Leukocyte Common Antigen), a universal membrane marker found on all myeloid and lymphoid cells (white blood cells), as well as essential complementary markers: an epithelial marker such as cytokeratin (Pan-CK) and a stromal/neural marker such as S-100. The package aims to answer the fundamental question: Is the tumor derived from blood cells (CD45-positive), epithelial tissue (CK-positive), or another tissue (such as melanocyte/neural, S-100-positive)?