The Gold Standard Consultative Package is a comprehensive and systematic immunohistochemical analysis of twelve predefined or case-specific immunohistochemical markers using immunohistochemical (IHC) technology. The review is conducted by a multidisciplinary, senior expert advisory panel, employing standardized diagnostic algorithms (such as those used in NCCN-guided centers) and correlating the results with the latest evidence-based practice. The package aims to produce a standardized "final opinion report" that serves as a reliable diagnostic document for local and international treatment and advanced clinical trials.