Question 1

Purpose of the Test

Accepted Answer

Determine if the tumor expresses high levels of the HER2 protein. Confirm HER2 gene amplification in borderline cases using FISH technology. Assist oncologists in selecting appropriate targeted therapies like Trastuzumab.

Question 2

Target Groups

Accepted Answer

Patients newly diagnosed with invasive breast cancer. Patients with advanced gastric or gastroesophageal junction cancer. Recurrent cancer cases to re-evaluate treatment options.

Question 3

Clinical Significance

Accepted Answer

Identifies candidates for anti-HER2 targeted biological therapies. Helps avoid unnecessary conventional chemotherapy side effects. Improves survival rates through personalized precision medicine.

Precision HER2 Testing for Oncology - HER2/neu Testing by IHC and FISH