Globulins are a component of total plasma proteins, comprising a diverse group of important proteins primarily produced in the liver and immune cells. This group includes antibodies (immunoglobulins such as IgG, IgA, and IgM), transport proteins (such as transferrin), and complement proteins. Globulin levels are typically calculated by subtracting albumin levels from the total protein count. Measuring globulin levels helps assess immune and liver function and detect infections or myeloid diseases.