Gabapentin analysis in serum using liquid chromatography–tandem mass spectrometry (LC-MS/MS) is an important test for determining the levels of this drug in the body. Gabapentin is commonly used to treat conditions such as neuropathic pain and epilepsy, helping to reduce seizures and alleviate nerve-related pain. The test is performed by drawing a blood sample, which is then analyzed in the laboratory using precise techniques to determine gabapentin levels. Measuring these levels helps doctors assess treatment effectiveness, adjust doses according to patient needs, and ensure there are no side effects or interactions with other medications. The results of this test are essential for understanding how a patient responds to therapy, with high levels potentially indicating an overdose, while low levels may reflect an insufficient dose to achieve the desired therapeutic effect. This analysis is an important tool for ensuring the safety and effectiveness of treatment in patients taking gabapentin.