Clobazam Serum by Liquid Chromatography–Tandem Mass Spectrometry (LC-MS/MS) is a laboratory test designed to measure the level of clobazam in a blood sample. Clobazam is used as an adjunct treatment for anxiety disorders and seizures, and it works by enhancing the effects of central nervous system depressants. This analysis is considered an important tool for monitoring the drug concentration in serum, helping physicians evaluate treatment effectiveness and accurately adjust dosages. The test also allows detection of potential interactions with other medications, contributing to improved therapeutic safety. The sample is collected using a simple method, and the results are essential to ensure that patients receive the optimal dose of clobazam.