CSF Leak Detection Test - Beta-2 Transferrin Test

This test measures the presence and quantity of Beta-2 Transferrin protein, an isoform of transferrin found exclusively in Cerebrospinal Fluid (CSF) and intraocular fluid (vitreous humor). It is not present in blood serum, plasma, tears, or normal nasal secretions. Detection relies on gel electrophoresis protein separation with immunofixation or immunodetection techniques, making this marker nearly 100% specific for confirming CSF leak.