AST Liver & Muscle Enzyme Test - Aspartate Aminotransferase (AST) Test

Aspartate aminotransferase (AST) levels, formerly known as serum glutamic oxaloacetic aminotransferase (SGOT), are measured. This enzyme is found in high concentrations in liver cells, heart (myocardium), skeletal muscle, kidneys, and brain cells. When these tissues are damaged or inflamed (such as in hepatitis, heart attack, or muscle injury), AST is released into the bloodstream, leading to elevated levels. It is often interpreted in conjunction with alanine aminotransferase (ALT) levels to help determine the source of the damage.