Dermatomyositis Antibody Test - Anti-Mi-2 Antibody Test

A serological test detects autoantibodies directed against a nuclear protein complex called Mi-2. These antibodies are primarily associated with the classic form of dermatomyositis. They are present in approximately 10–30% of adult dermatomyositis patients, and at a higher rate in children. They are a characteristic marker of this disease and are rarely seen in other connective tissue disorders or in isolated polymyositis.