Question 1

Purpose of the Profile

Accepted Answer

Diagnose Acromegaly in adults. Screen for Gigantism in children and adolescents. Evaluate pituitary gland function regarding growth hormone secretion. Monitor treatment efficacy for growth hormone disorders.

Question 2

When to Perform This Test?

Accepted Answer

Abnormal increase in hand or foot size. Changes in facial features such as enlarged jaw or nose. Chronic joint pain and shortness of breath. Excessive and rapid height growth in children.

Question 3

Procedure Steps

Accepted Answer

An initial blood sample is taken to measure IGF-1. The patient consumes a standardized glucose solution. Serial blood samples are taken at specific intervals to monitor GH suppression. The procedure requires staying at the lab for 2-3 hours.

Acromegaly and Growth Hormone Screening - Acromegaly Screening Profile (IGF-1 & GH)