Cocaine Metabolites Confirmation, Urine, Quantitative by Gas Chromatography–Mass Spectrometry (GC/MS) is used to detect the presence and levels of cocaine metabolites in urine samples. Cocaine is considered a stimulant substance that affects the central nervous system and has negative effects on physical and mental health. This analysis provides high accuracy in detecting the presence of cocaine and its derivatives, such as benzoylecgonine (BZE) and other compounds, helping physicians evaluate a history of cocaine use. This test is used in many contexts, including medical examinations, treatment programs, and legal investigations. The results of this analysis are considered an important tool in making therapeutic decisions and ensuring patient safety, as they help detect poisoning or excessive use and promote awareness of the health consequences of cocaine use.