Myogenin Rhabdomyosarcoma Test - Myogenin Immunohistochemistry Test

Immunohistochemical assay for myogenin (myogenic differentiation 1) aims to detect this key early nuclear transcription factor for skeletal muscle differentiation. Myogenin is a highly specific and sensitive marker of skeletal muscle differentiation and is currently the gold standard for confirming the histological diagnosis of rhabdomyosarcoma (RMS). It is expressed exclusively in the nuclei of cells undergoing skeletal muscle differentiation.