A hemoglobin test (Hemoglobin - Hb or Hgb) measures the concentration of hemoglobin protein in the blood. Hemoglobin is the main protein in red blood cells, responsible for carrying oxygen from the lungs to all body tissues and returning carbon dioxide from the tissues to the lungs for elimination. Measuring hemoglobin is the most important and common part of evaluating anemia, as it reflects the blood's ability to carry oxygen.