5-HIAA Test (5-Hydroxyindoleacetic Acid) is a laboratory analysis used to measure 5-HIAA levels in urine or plasma. This test is important for evaluating neuroendocrine tumors, particularly adrenal gland tumors and carcinoid syndrome, where the body produces excessive amounts of serotonin. The test is usually performed using high-performance liquid chromatography (HPLC) to provide accurate and rapid results. This analysis can help physicians diagnose serotonin-related disorders and monitor the effectiveness of treatments. Patients are advised to avoid certain foods and medications before the test to ensure reliable results.