This immunohormonal diagnostic package is designed to evaluate breast and female reproductive tract tumors. It primarily focuses on measuring progesterone receptor (PR) expression, a nuclear transcription factor expressed in progesterone-responsive cells. The package also assesses estrogen receptor (ER) and the cytogenetic marker Ki-67, and additional markers such as HER2 or BCL2, depending on the context. The package aims to determine the tumor's hormonal status, approximate molecular subtype classification, and estimate the expected response to hormonal therapy (e.g., tamoxifen, aromatase inhibitors).